In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 71759-87-0, name is 4-Iodo-1-methyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C4H5IN2
To a microwave tube was added 4-iodo-l -methyl- 1H-imidazole (2.00 g, 9.62 mmmol) and CuCN (1.03 g, 11.5 mmol) in DMA (12 mL). The reaction mixture was heated at 180 C in a microwave reactor for 45 min. The reaction mixture was concentrated in vacuo. The residue was suspended in EtOAc/sat. NH4Cl/NH4OH (add NH4OH to sat NH4Cl to pH=9) and stirred for 30 min. The organic phase was separated, washed with brine, dried over anhydrous Na2SO4, filtered and concentrated to afford 580 mg of the title compound as a light brown solid.
The synthetic route of 71759-87-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2009/70485; (2009); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem