In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 28890-99-5, name is 5H-Benzo[d]benzo[4,5]imidazo[1,2-a]imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Recommanded Product: 28890-99-5
A.) 20.0 g (87.3 mmol) 3-bromo-benzonitrile, 16.6 g (80.0 mmol) 6H-benzimidazolo[1 ,2- a]benzimidazole, 67.9 g (320 mmol) potassium phosphate tribasic, 1.5 g (7.88 mmol) cupper(l) iodide and 100 g (875 mmol) DACH ((±)-trans-1 ,2-diaminocyclohexane) in 240 ml dioxane are stirred at 100 C under nitrogen for 7 h. The reaction mixture is filtered hot and the solids are washed with dioxane. The reaction mixture is cooled to 50 C and the crystalized product is filtered of and is washed with methanol. Yield 1 1 .2 g (46 %) 1H-NMR (300 MHz, CDCI3): delta 7.33-7.49 (m, 4H), 7.59 – 7.63 (d, 1 H), 7.72-7.83 (m, 3H), 7.86- 7.90 (d, 2H), 8.22-8.26 (m, 2H),
The synthetic route of 28890-99-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; IDEMITSU KOSAN CO., LTD.; RAIMANN, Thomas; SCHAeFER, Thomas; SAITO, Masatoshi; WOLLEB, Heinz; BENEDITO, Flavio Luiz; NISHIMAE, Yuichi; NAKANO, Yuki; NAGASHIMA, Hideaki; (111 pag.)WO2016/157113; (2016); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem