Simple exploration of 1072-62-4

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1072-62-4.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1072-62-4, name is 2-Ethyl-1H-imidazole, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 1072-62-4

In an argon stream, 2-ethylimidazole (1.92 g, 20 mmol) and sodium hydride (0.84 g, 21 mmol) were suspended in tetrahydrofuran (30 mL) and cooled to 0 C. 1-Iodohexane (4.67 g, 22 mmol) was added to the suspension, and the mixture was stirred at room temperature for 30 minutes and then at 75 C. for 24 hours. After standing to cool, diethyl ether and water were added to the reaction mixture, the organic layer was extracted, and the organic layer was washed with brine. After adding sodium sulfate to the organic layer and stirring, the solid was filtered off and the solvent was distilled off. The resulting oily substance was purified by silica gel column chromatography (chloroform / methanol = 10: 1) to obtain 1-hexyl-2-ethylimidazole as a yellow oily substance (2.93 g, 81%).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1072-62-4.

Reference:
Patent; Tosoh Corporation; Sagami Chemical Research Institute; Aihara, Hidenori; Yamagata, Takuya; Hachiya, Hitoshi; Watanabe, Makoto; Fukuda, Takashi; Ueda, Saori; Miyashita, Masato; (64 pag.)JP2018/168149; (2018); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem