Some tips on 3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde

The synthetic route of 870837-18-6 has been constantly updated, and we look forward to future research findings.

870837-18-6, name is 3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Application In Synthesis of 3-Methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde

A mixture of 3-methoxy-4-(4-methyl-1 H-imidazol-1-yl)benzaldehyde (1.22 g, 5.64 mmol), F3 (4.30 g), piperidine (1.4 mL), and ethanol (23 ml_) was heated to 85 C for 3 h. The resulting solution was absorbed onto silica gel (18 g) and chromatographed (MeOH/aq. NH4OH/CH2CI2) to afford slightly impure compound F4 (3.59 g) as a brown foam. MS (M+1 )+ m/z calcd for C40H42FN4O3SSi+ = 705.3, found m/z = 705.4.

The synthetic route of 870837-18-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; SCHERING CORPORATION; WO2009/20580; (2009); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem