Synthetic Route of 760212-58-6, The chemical industry reduces the impact on the environment during synthesis 760212-58-6, name is 1-(4-Bromophenyl)-2-phenyl-1H-benzo[d]imidazole, I believe this compound will play a more active role in future production and life.
Fifth Step: Synthesis of Intermediate Product (E) (0135) 22.4 g (64.1 mmol) of the intermediate product (D), 19.6 g (77.0 mmol) of bis(pinacolato)diboron, 1.3 g (1.6 mmol) of [1,1?-bis(diphenylphosphino)ferrocene]dichloropalladium (II), and 18.9 g (192.3 mmol) of potassium acetate were suspended in 230 mL of dimethylformamide and agitated at 80 C. for 12 hours. After cooling, the reaction solution was poured in distilled water to deposit a solid, which was filtered and separated. The filtered solid was recrystallized with ethyl acetate/hexane to provide 24.4 g (yield: 96%) of intermediate product (E).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-(4-Bromophenyl)-2-phenyl-1H-benzo[d]imidazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; CHEIL INDUSTRIES, INC.; Jung, Ho-Kuk; Kang, Dong-Min; Kang, Myeong-Soon; Kang, Eui-Su; Kim, Nam-Soo; Lee, Nam-Heon; Chae, Mi-Young; (60 pag.)US9548460; (2017); B2;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem