Application of 52099-72-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 52099-72-6, name is 1-(Prop-1-en-2-yl)-1H-benzo[d]imidazol-2(3H)-one, This compound has unique chemical properties. The synthetic route is as follows.
Preparation 7; Ethyl 4-(3-isopropenyl-2-oxo-2.3-dihydro-1H-benzimidazol-1-yl)butanoate; A mixture of the compound of Preparation 8 (114.0 g, 0.7 mol), potassium carbonate (136 mg, 1 mol) and the compound of Preparation 166 (167.4 g, 0.9 mol) in acetone (500 ml) was heated under reflux for 18 h. The reaction mixture was then cooled to room temperature and filtered, washing through with acetone (250 ml). The filtrate was concentrated in vacuo and the residue was dried overnight at 40C to give the title compound (223.8 g).1H-NMR (d6-DMSO): 1.10 – 1.20 (3H), 2.10 – 2.15 (3H), 3.95 – 4.07 (2H), 5.10 – 5.12 (1 H), 5.35 – 5.39 (1 H), 7.00 – 7.10 (3H), 7.20 – 7.26 (1 H)
The chemical industry reduces the impact on the environment during synthesis 1-(Prop-1-en-2-yl)-1H-benzo[d]imidazol-2(3H)-one. I believe this compound will play a more active role in future production and life.
Reference:
Patent; PFIZER LIMITED; WO2008/44127; (2008); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem