4856-97-7, name is (1H-Benzoimidazol-2-yl)methanol, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Formula: C8H8N2O
The intermediate 1H-benzimidazole-2-methanol (1 g, 1 eq) and potassium permanganate (2.6 g. 1.5 eq) were added to dilute sodium hydroxide solution and heated at 100 ° C under reflux.After the reaction was completed, it was cooled to room temperature, the pH was adjusted to be acidic, and a brown solid was precipitated.Yield: 86percent.
The synthetic route of 4856-97-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; China Pharmaceutical University; Wang Jinxin; Shang Yanguo; Yu Jing; (20 pag.)CN110105286; (2019); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem