Extracurricular laboratory: Synthetic route of 614-97-1

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Methyl-1H-benzo[d]imidazole, other downstream synthetic routes, hurry up and to see.

Related Products of 614-97-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 614-97-1, name is 5-Methyl-1H-benzo[d]imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.

General procedure: Equimolar quantities of the 7-bromo alkane derivatives (2a-2c) and corresponding benzimidazole were dissolved in acetone (30 mL), and certain amount of K2CO3 was also added to the solution. The solution was then refluxed for approximately 12 h. The product was extracted by dichloromethane. Then evaporated of the solvent, the residue was purified bycolumn chromatography on silica gel, eluting with dichloromethane/methanol (30:1) to givethe compounds 3-23.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Methyl-1H-benzo[d]imidazole, other downstream synthetic routes, hurry up and to see.

Reference:
Article in Press; Wang, Zhe; Deng, Xiangping; Xiong, Shujuan; Xiong, Runde; Liu, Juan; Zou, Liu; Lei, Xiaoyong; Cao, Xuan; Xie, Zhizhong; Chen, Yanming; Liu, Yunmei; Zheng, Xing; Tang, Guotao; Natural Product Research; (2017); p. 1 – 10;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem