Related Products of 760212-58-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 760212-58-6, name is 1-(4-Bromophenyl)-2-phenyl-1H-benzo[d]imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
Step S101: 2-phenyl-4-N-p-bromophenylbenzimidazole was dissolved in THF (tetrahydrofuran); preferably,In the step, 2-phenyl-4-N-p-bromophenylbenzimidazole was 1. Ommol, THF (tetrahydrofuran)Step S102: cooling to -78 C, adding n-butyllithium, for one hour; preferably, n-butyllithium is 1 ยท lmmol in this step;Step S103: Diphenylphosphonium chloride is added and the temperature is raised to room temperature for 12 hours. Preferably, diphenylphosphonium chloride is 1.2 mmol in this step;Step S104; adding a methanol quenching reaction while adding 30% H2O2 aqueous solution to give 4- (1-methylbenzimidazolyl) -triphenylphosphine oxide; preferably, 30% H2O2 aqueous solution in this step is 5 ml ; Yield: 70%
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-(4-Bromophenyl)-2-phenyl-1H-benzo[d]imidazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Wuhan Shang Sai Optoelectric Technology Co., Ltd.; Wang Lei; Pan Biao; Wang Bo; Mu Guangyuan; (19 pag.)CN104370964; (2017); B;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem