Electric Literature of 10111-08-7, These common heterocyclic compound, 10111-08-7, name is Imidazole-2-carboxaldehyde, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Sodium carbonate (1.10 g, 10.4 mmol) was added to a solution of hydroxylamine hydrochloride (1.44 g, 20.7 mmol) in water (5 ml) and adjusted to pH 7. Imidazole-2-carboxaldehyde (1,1.00 g, 10.4 mmol) was added potionwise to resulting reaction mixture. After being stirred for 1 h at 70 C, the product was filtered, washed with cold water and dried in vacuo to give a white solid (0.83 g, 72%).
Statistics shows that Imidazole-2-carboxaldehyde is playing an increasingly important role. we look forward to future research findings about 10111-08-7.
Reference:
Article; Kim, Tae Keun; Lee, Byung Woo; Lee, Hai Whang; Chung, Kyoo-Hyun; Kim, Jin Seuk; Bulletin of the Korean Chemical Society; vol. 34; 6; (2013); p. 1864 – 1866;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem