Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3034-42-2, name is 1-Methyl-5-nitroimidazole, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C4H5N3O2
General procedure: To a solution of 1-methyl-5-nitro-1H-imidazole (10 g, 0.078 mol) in EtOH (400 mL) was added wet10% Pd/C (2 g), and the mixture was stirred at room temperature for 1 hr. Then diethyl 2- (ethoxymethylene)malonate (20 g, 0.094 mol) was added. The mixture was stirred under H2 for overnight. Pd/C was removed after filtration and the solvent was evaporated in vacuum. The residue was purified by flash column (DCM/MeOH = 10/1) to give diethyl 2-(((1-methyl-1H-imidazol-5-yl)amino)methylene)malonate (6 g, yield: 28.7%) as brown oil. MS: m/z 268.1 (M+H).
According to the analysis of related databases, 3034-42-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE; PINKERTON, Anthony, B.; HASSIG, Christian, A.; JACKSON, Michael, R.; ARDECKY, Robert, John; PASS, Ian; (436 pag.)WO2016/123392; (2016); A2;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem