Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1072-62-4, name is 2-Ethyl-1H-imidazole, A new synthetic method of this compound is introduced below., Formula: C5H8N2
(a) 3-[3-(2-Ethylimidazol-l-ylmethyl)phenyl]-5-z^o-butyl-7V-fe7Y-butylthiophene- 2-sulfonamide; To a solution of 3-(3-bromomethylphenyl)-5-ziO-butyl-7V-fe7t-butylthiophene-2- sulfonamide (70 mg, 0.158 mmol; see Example l(e)) in dioxane (2.0 mL) was added 2-ethylimidazole (45.4 mg, 0.473 mmol) and the reaction mixture was stirred for 1 h at 80C. The reaction mixture was concentrated in vacuo and the residue was purified by flash chromatography using MeOH:CH2Cl2 (6:94) as EPO
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; VICORE PHARMA AB; WO2006/109048; (2006); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem