In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 7098-07-9, name is 1-Ethyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. SDS of cas: 7098-07-9
1-Ethyl-2-iodo-1H-imidazole ; [Show Image] (1) To a solution of 1-ethyl-1H-imidazole (2.844 g) in THF (60 ml), n-BuLi (11.6 ml, 2.59 N in hexane) was added dropwise at -78C under an argon atmosphere. After stirring at the same temperature for 30 minutes, a solution of I2 (7.614 g) in THF (25 ml) was added dropwise. The reaction mixture was warmed to room temperature, diluted with saturated aqueous sodium bicarbonate, and extracted with AcOEt. After washing with saturated aqueous Na2S2O3, the organic layer was dried over MgSO4, filtered and then evaporated to remove the solvent, thereby giving the titled compound (6.492 g) as a light-yellow solid. 1H NMR (200 MHz, CDCl3) delta ppm: 1.40(t,J=7.4Hz,3H), 3.95(q,J=7.4Hz,2H), 7.02-7.06(m,1H), 7.07-7.11(m,1H
The synthetic route of 7098-07-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; TAISHO PHARMACEUTICAL CO., LTD; EP1988081; (2008); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem