Reference of 35203-44-2, These common heterocyclic compound, 35203-44-2, name is 1-Propyl-1H-imidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
2.2.2 Synthesis of [Ru(eta6-p-cymene)(N-PrIm)Cl2] (2) The [Ru(eta6-p-cymene)(N-PrIm)Cl2] was synthesized following the literature method of Vock et al [10] . To a suspension of [Ru-(eta6-p-cymene)Cl2]2 (0.199?g, 0.326?mmol) in toluene (30?mL), N-Propylimidazole (0.0756?mL, 0.652?mmol) was added at room temperature. The resulting mixture was heated and refluxed for 3?h. After, the mixture was cooled, and the precipitate was filtered. Crystals suitable for X-ray structure analysis were obtained from toluene filtrate (109.5?mg, yield: 40.32percent). Melting point?=?198?°C. Anal. Cal. for C16H24N2Cl2Ru (Mw?=?416.34) C: 46.16, H: 5.81, N: 6.73; found: C: 46.66, H: 5.69, N: 6.58percent. 1HNMR (200?MHz, CDCl3): delta(ppm) 0.93 (t, 3H, 3″-H3), 1.28 (d, 6H, 1-CH(CH3)2), 1.70-1.89 (m, 2H, 2″-H2), 2.19 (s, 3H, 4-CH3), 2.97 (sept, 1H, 1-CH(CH3)2), 3.85 (t, 2H, 1″-H2), 5.24 (d, 2H, 2-H, 6-H), 5.44 (d, 2H, 3-H, 5-H), 6.88 (t, 1H, 4′-H), 7.32 (t, 1H, 5′-H), 7.90 (t, 1H, 2′-H). 13CNMR (50?MHz, CDCl3): delta(ppm) 11.02 (C-3″), 18.51 (4-CH3), 22.28 (1-CH(CH3)2), 23.92 (1-CH(CH3)2), 30.71 (C-2″), 49.89 (C-1″), 81.39 (C-2, C-6), 82.67 (C-3, C-5), 97.36 (C-4), 102.54 (C-1), 119.36 (C-4′), 132.16 (C-5′), 139.78 (C-2′). IR (KBr, pellet): nu (cm-1) 3143, 3110, 3044 (nu=CH), 2958, 2931, 2874 (nuCH), 1618 (nuC=N), 1533, 1520, 1498 (nuC=C). UV-Vis (H2O, C?=?10-4 M): lambdamax/nm (epsilon/L mol-1 cm-1): 254 (3005.21), 307 (1865.98) and 393 (1123.65).
Statistics shows that 1-Propyl-1H-imidazole is playing an increasingly important role. we look forward to future research findings about 35203-44-2.
Reference:
Article; Djuki?, Maja; Jeremi?, Marija S.; Jeli?, Ratomir; Klisuri?, Olivera; Koji?, Vesna; Jakimov, Dimitar; Djurdjevi?, Predrag; Matovi?, Zoran D.; Inorganica Chimica Acta; vol. 483; (2018); p. 359 – 370;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem