In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1072-63-5, name is 1-Vinyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. COA of Formula: C5H6N2
1-vinyl imidazole (5.18 g, 55 mmol) and 1,6-dibromohexane (2.79 g, 22 mmol) were dissolved in methanol (50 mL) in a round-bottom flask fitted with a condenser and N2 bubbler. Subsequently, the mixture was stirred at 80 C for 48 h under a nitrogen atmosphere. After then, the reaction mixture was precipitated from diethyl ether (150 mL), and recrystallized twice from diethyl ether. The products were dried under vacuum for 24 h at R.T. [C6VIm]Br was obtained as white solid. Yield: 71%. [C6VIm]Br: 1H-NMR (D2O, 400 MHz, ppm):7.57 (1H, s); 7.37 (1H, s); 6.93 (1H, m); 5.60 (1H, d); 5.22 (1H, d); 4.04 (2H, t); 1.70 (2H, s); 1.17 (2H, s).1H-NMR (DMSO, 400 MHz, ppm): 9.66 (1H, s); 8.24 (1H, t); 7.99 (1H, t); 7.33 (1H, m); 5.99 (1H, m);5.43 (1H, m); 4.22 (2H, t); 1.83 (2H, d); 1.31 (2H, s). 13C-NMR (DMSO, 100 MHz, ppm): 135.36,128.88, 123.31, 119.23, 109.04, 49.02, 28.80, 24.77. ESI-MS (m/z): calcd. for C16H24N4Br2: 432.2,found: 432.2. Elemental analysis (%): Calculated: C, 44.46; H, 5.60; N, 12.96; Br, 36.98. Found: C,42.94; H, 5.36; N, 12.50; Br, 39.20. M.P.: 219 C.
The synthetic route of 1072-63-5 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Zhang, Jing; Liu, Jingjiang; Zuo, Yong; Wang, Rongmin; Xiong, Yubing; Molecules; vol. 20; 9; (2015); p. 17378 – 17392;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem