Application of 2302-25-2, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2302-25-2 as follows.
Palladium on carbon (2 g, 10% Pd)Stirring in hydrogen for one hour,And then dissolved in pure heavy water (50 g, 2.5 mol) Of 4-bromoimidazole (10 g, 69 mmol) was added,After hydrogen addition, the mixture was stirred at 100 C for 1 h,The reaction solution was filtered to remove the catalyst,Rotate the solvent to give compound 11 (9.2 g, yield 91%),
According to the analysis of related databases, 2302-25-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Hinova Pharmaceuticals Inc.; Fan, Lei; Chen, Ke; Li, Xinghai; Chen, Yuanwei; (24 pag.)CN106256830; (2016); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem