Adding a certain compound to certain chemical reactions, such as: 621-72-7, name is 2-Benzyl-1H-benzo[d]imidazole, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 621-72-7, Recommanded Product: 621-72-7
To the reaction vessel was added 8.2 g of dibazole,63 g of 10 wt% hydrochloric acid solution and 1.2 g of activated carbon,Air was introduced into the reaction vessel while stirring, and the temperature was raised to 95 C.The reaction was stirred for 10 hours while the reaction was completed, and the air was stopped.Drop to 15 C, filter, and evaporate the filtrate under reduced pressure to give 8.5 g of crude material;The crude product was mixed with 70 g of anhydrous methanol and stirred and dissolved at 55 C.The mixture was filtered while hot, and the filtrate was stirred at 0 C for 3 hours, and filtered.Drying, 7.8 g of diazol oxidized impurity reference substance was obtained, and the yield was 89.3%.The purity was determined by HPLC to be 99.95%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Benzyl-1H-benzo[d]imidazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Wuhan Xian Lu Pharmaceutical Technology Co., Ltd.; Huang Li; Ning Fan; Wu Bo; Wang Ge; Xie Shuwei; Chen Weijiang; (6 pag.)CN108863946; (2018); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem