Electric Literature of 52099-72-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 52099-72-6, name is 1-(Prop-1-en-2-yl)-1H-benzo[d]imidazol-2(3H)-one, This compound has unique chemical properties. The synthetic route is as follows.
1-isopropenylbenzimidazolone (0.5 g, 2.9 mmol) in DMA (8 niL) was added and trimethyl-(4- methyl-benzo[&]thiophen-3-ylmethyl)-ammonium; iodide (1.0 g, 2.9 mmol) and K2CO3 (0.80 g, 5.74 mmol). The reaction mixture was heated to 120 0C for 15 min in a microwave and then 150 0C for another 5 min. The mixture was diluted with ethyl acetate and washed with water (x4). The organic phase was dried over Na2SO4 and concentrated. The resulting residue was purified by silica gel prep TLC using 98:2 CH2CkMeOH as an eluent to afford 0.7 g of the desired product as a white solid
The chemical industry reduces the impact on the environment during synthesis 1-(Prop-1-en-2-yl)-1H-benzo[d]imidazol-2(3H)-one. I believe this compound will play a more active role in future production and life.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2008/147697; (2008); A1;,
Imidazole – Wikipedia,
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