Related Products of 14741-71-0,Some common heterocyclic compound, 14741-71-0, name is Ethyl 2-(1H-benzo[d]imidazol-2-yl)acetate, molecular formula is C11H12N2O2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: Et3N(4 mmol) was added dropwise to a stirred solution of the benzimidazole (1.5 mmol) and the dichloride compound 1(2 mmol) in CH2Cl2 (3 mL) at 0 C. The resulting mixture was stirred at room temperature overnight and worked up as for Method A.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route Ethyl 2-(1H-benzo[d]imidazol-2-yl)acetate, its application will become more common.
Reference:
Article; Innes, Dylan; Perkins, Michael V.; Liepa, Andris J.; Francis, Craig L.; Australian Journal of Chemistry; vol. 71; 1; (2018); p. 58 – 69;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem