Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 16042-25-4, name is 2-Imidazolecarboxylic acid, A new synthetic method of this compound is introduced below., HPLC of Formula: C4H4N2O2
60 g of N,N-dimethylformamide as a solvent and Zn(OAc)2 and benzimidazole in a molar ratio of 1:1.5 were placed in a flask. The reaction was allowed to proceed at 130 C. for 24 h. The resulting solid was collected by filtration. The solid was precipitated in N,N-dimethylformamide, collected, and dried under vacuum at 180 C. for 3 h to afford Zn(benzimidazole)1.6(OAc)0.4 as a zinc-imidazole complex mixed catalyst. The catalyst was analyzed by Fourier-transform infrared (IR) spectroscopy and X-ray diffraction (XRD) and the results are shown in FIGS. 1-3.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY; LEE, Hyun Joo; Jae, Jungho; Kim, Hong Gon; Dahnum, Deliana; Cho, Shinhye; (14 pag.)US2020/61596; (2020); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem