Research on new synthetic routes about 32673-41-9

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Imidazolemethanol hydrochloride, other downstream synthetic routes, hurry up and to see.

Related Products of 32673-41-9, The chemical industry reduces the impact on the environment during synthesis 32673-41-9, name is 4-Imidazolemethanol hydrochloride, I believe this compound will play a more active role in future production and life.

(a) [1-(4-Chlorobenzyl)-1H-imidazol-4-yl]methanol 4-Chlorobenzylchloride (1.2 g) was dissolved in N,N-dimethylformamide (20 ml), 4(5)-hydroxymethylimidazole hydrochloride (1.0 g) and potassium carbonate (4 g) were added and the mixture heated at 90 C. for 20 hours. Water and ethyl acetate were added, the organic phase was separated, washed with brine, dried and the solvent removed by evaporation. The residue was purified by chromatography (dichloromethane:methanol, 9:1) to give the product as a mixture of regioisomers (0.5 g). This material was used in the next step without further purification.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Imidazolemethanol hydrochloride, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; AstraZeneca UK Limited; US6566376; (2003); B1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem