Adding a certain compound to certain chemical reactions, such as: 22884-10-2, name is 2-(1H-Imidazol-1-yl)acetic acid, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 22884-10-2, Product Details of 22884-10-2
Step 1: methyl 14-cyclohexl-3-fluoro-6-( 1 H-imidazol-1 -ylacetyl)-5.6,7,8-tetrahydroindolo[2.] -a] (2,5 lbenzodiaz.ocine-11 -carboxylate; To a solution of 1 eq of methyl-14-cyclohexyl-3-fluoro-5,6,7,8-tetrahydroindolo[2,l- a][2,5]benzodiazocin-l 1-carboxylate (prepared as described in Example 18, Step 5 ) in DCM (0.06 M), 1.1 eq of imidazo-1-yl acetic acid in DCM (0.05 M), 3 eq of DIPEA and 1.5 eq of TBTU were added and the mixture stirred at RT overnight. Volatiles were removed in vacuo and the crude material was used in the next step without further purification; MS (ES+) m/z 515 (M+Eta)+. EPO
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(1H-Imidazol-1-yl)acetic acid, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA; WO2006/46030; (2006); A2;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem