Share a compound : 1-(4-Nitrophenyl)-1H-imidazole

According to the analysis of related databases, 2301-25-9, the application of this compound in the production field has become more and more popular.

Related Products of 2301-25-9, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 2301-25-9 as follows.

YB112 (162mg) was dissolved in THF solvent. After the reaction system was deaerated,10% Pd / C 20mg was added.A hydrogen balloon was added to the reaction system, and the reaction was allowed to proceed overnight.The reaction was filtered and washed with ethyl acetate, concentrated, and the target product YB126 (154 mg) was purified on a silica gel column.

According to the analysis of related databases, 2301-25-9, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Zhao Yujun; Li Jia; Wang Zengtao; Zhang Shiyan; Zang Yi; Wang Peipei; Sun Dandan; Zhang Hanyan; (155 pag.)CN110818683; (2020); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem