Electric Literature of 2302-25-2, The chemical industry reduces the impact on the environment during synthesis 2302-25-2, name is 4-Bromo-1H-imidazole, I believe this compound will play a more active role in future production and life.
4-Bromoimidazole (0.30 g, 2.04 mmol) was added to a 150 mL round bottom flask using potassium carbonate as a base (0.32 g,2.35 mmol), acetonitrile was stirred at 70 C for 30 minutes, and after cooling to room temperature, compound III (0.40 g,1.57 mmol) continued to warm to 70 C reaction, and thin layer chromatography was followed until the reaction was completed. After concentration, extraction, column chromatography separation,After drying and the like, the compound I-1-8 (0.34 g) was obtained, yield 53.7%; white solid
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Bromo-1H-imidazole, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Southwest University; Zhou Chenghe; Man Nabaonei·lamohan·laao·yadafu; Hu Yuanyuan; (25 pag.)CN108863964; (2018); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem