Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 137049-00-4, name is 1-Methyl-1H-imidazole-4-sulfonyl chloride, This compound has unique chemical properties. The synthetic route is as follows., Formula: C4H5ClN2O2S
General procedure: NaH (6.7 mg, 0.28 mmol) was suspended in dry DMF.6-(1-methyl-1H-pyrazol-4-yl)-1H-pyrazolo[4,3-b]pyridine (39, 50 mg, 0.25 mmol) was added intothe above solution slowly at 0 C. Then, the cooling solution was stirred for 0.5 h. Subsequently,6-chloroimidazo[2,1-b]thiazole-5-sulfonyl chloride (77 mg, 0.3 mmol) was added and stirred for another 4 h at room temperature. Then, water (30 mL) was added to the reaction system. The reactionmixture was extracted with ethyl acetate (3 40 mL). The combined organic phase was washed withsaturated salt water (3 40 mL), dried over anhydrous Na2SO4, filtered, and concentrated underreduced pressure to give the corresponding crude target product, which was purified by flash columnchromatography with dichloromethane/methanol to afford compound 5 as a white hairy solid withthe yield of 78%.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 137049-00-4.
Reference:
Article; Jiang, Alan; Liu, Qiufeng; Wang, Ruifeng; Wei, Peng; Dai, Yang; Wang, Xin; Xu, Yechun; Ma, Yuchi; Ai, Jing; Shen, Jingkang; Ding, Jian; Xiong, Bing; Molecules; vol. 23; 3; (2018);,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem