Continuously updated synthesis method about 4-Imidazol-1-yl-benzaldehyde

According to the analysis of related databases, 10040-98-9, the application of this compound in the production field has become more and more popular.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 10040-98-9, name is 4-Imidazol-1-yl-benzaldehyde, This compound has unique chemical properties. The synthetic route is as follows., Formula: C10H8N2O

General procedure: The 4-alkyl(aryl)aminobenzaldehyde (1 mmol) was added to(RMe2Si)3CLi, R=H,Me (1 mmol) in THF under argon. The mixturewas reacted according to Tables 1 and 2. The reaction was quenchedwith H2O, extracted with CH2Cl2 and dried over Na2SO4. The solventwas evaporated under reduced pressure and the residue was purifiedby preparative column chromatography (n-hexane/ethylacetate) andthe corresponding products were obtained.

According to the analysis of related databases, 10040-98-9, the application of this compound in the production field has become more and more popular.

Reference:
Article; Safa, Kazem Dindar; Nadimi, Sanaz; Alyari, Maryam; Journal of Chemical Research; vol. 38; 8; (2014); p. 498 – 501;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem