Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 17325-26-7, name is Methyl 1H-imidazole-5-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: Methyl 1H-imidazole-5-carboxylate
To a stirred solution of methyl 4-imidazolecarboxylate (CAS Number 17325-26-7; 0.500 g,3.97 mmol) and 1,10-phenanthroline (1.400 g, 7.94 mmol) in DMSO (5 ml) was added iodobenzene(1.600 g, 7.94 mmol), Cs2CO3 (3.800 g, 11.9 mmol) and Cu20 (0.567 g, 3.97 mmol) at rt in a microwave tube. The reaction mixture was heated at 100C for 15 mm in microwave. The resulting reaction mixture was cooled to rt and filtered. The obtained filtrate was diluted with water (60 ml) and extracted with EtOAc (3 x 60 ml). The combined organic layer was dried over Na2SO4, filtered andconcentrated under reduced pressure yielding methyl 1 -phenyl- 1H-imidazole-4-carboxylate (0.450 g,2.23 mmol). This material was directly used for next step without any further purification. LCMS:Method C, 2.066 mi MS: ES+ 203.00.
According to the analysis of related databases, 17325-26-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MISSION THERAPEUTICS LIMITED; KEMP, Mark Ian; STOCKLEY, Martin Lee; MADIN, Andrew; (95 pag.)WO2017/103614; (2017); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem