In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 930-62-1, name is 2,4-Dimethylimidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. HPLC of Formula: C5H8N2
2, 4-dimethylimidazole (1.58 g, 16.45 mmol) was dissolved in N, N-dimethylamine (60 mE). In an ice bath, to the solution was added sodium hydride (60% in mineral oil) (1.05 g, 26.3 mmol) slowly. The reaction mixture was reacted for 30 minutes in an ice bath, and then in an ice bath the reaction solution was added dropwise to a solution of compound 1-c (5.0 g, 17.6 mmol) in N, N-dimethylformamide (100 mE) slowly. The reaction mixture was reacted at 0 C. for 10 minutes, and then diluted with ethyl acetate (300 mE). The organic layer was separated, washed with water, dried over anhydrous sodium sulfate, and concentrated under reduced pressure, to obtain 20-d (4.0 g, 71.0%). EC-MS (ESI): mlz=342.9, 344.9 (M+H7.
The synthetic route of 930-62-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SHANGHAI YINGLI PHARMACEUTICAL CO., LTD; XU, Zusheng; (174 pag.)US2016/214994; (2016); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem