Electric Literature of 149520-94-5, The chemical industry reduces the impact on the environment during synthesis 149520-94-5, name is Ethyl 2-amino-1H-imidazole-5-carboxylate, I believe this compound will play a more active role in future production and life.
a) Ethyl 7-oxo-5,6,7,8-tetrahydroimidazo[l,2-a]pyrimidine-2-carboxylateEthyl 2-amino-lH-imidazole-4-carboxylate (6.45 mmol, 1 g) and triethyl- amine (10.04 mmol, 1.016 g) were suspended in dry ACN (30 ml) and cooled to 0 C. Acryloyl chloride (9.67 mmol, 0.875 g) dissolved in dry ACN (4 ml) was added dropwise. The resulting mixture was slowly warmed to RT and subsequently heated to 50 C for 16 h. The solvent was evaporated and the residue purified by flash chromatography. 0.358 g of the title compound was obtained. lH-NMR (400 MHz, CDC13): delta 1.37 (t, 3H), 2.92 (t, 2H), 4.18 (t, 2H), 4.37 (q, 2H), 7.40 (s, IH), 8.78 (bs, IH).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Ethyl 2-amino-1H-imidazole-5-carboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; ORION CORPORATION; TOeRMAeKANGAS, Olli; WOHLFAHRT, Gerd; SALO, Harri; RAMASUBRAMANIAN, Rathna, Durga; PATRA, Pranab, Kumar; MARTIN, Arputharaj, Ebenezer; HEIKKINEN, Terhi; VESALAINEN, Anniina; MOILANEN, Anu; KARJALAINEN, Arja; WO2012/143599; (2012); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem