Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 37619-25-3, name is Methyl 1H-benzo[d]imidazole-4-carboxylate, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C9H8N2O2
[Step 2] Methyl 6-nitro-1H-benzimidazole-4-carboxylate Methyl 1H-benzimidazole-4-carboxylate (315 mg) was dissolved in conc. sulfuric acid (3 mL), and the solution was stirred on ice bath. A small amount of potassium nitrate (199 mg) was added portion-wise, the solution was stirred at room temperature for 4 hours. The reaction mixture was poured into ice, alkalified with 3N aqueous sodium hydroxide solution under stirring on ice bath, and extracted with ethyl acetate. The ethyl acetate layer was washed sequentially with water and brine, dried over anhydrous magnesium sulfate. The titled compound (334 mg) was obtained as colorless powder after distilling off a solvent under reduced pressure.
According to the analysis of related databases, 37619-25-3, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Nippon Shinyaku Co., Ltd.; OTSU, Hironori; EP2746265; (2015); B1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem