58442-17-4, name is 1H-Benzimidazole-5-carbaldehyde, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. SDS of cas: 58442-17-4
General procedure: 4.94g (56.7mmol) of MnO2 were added to a solution of 1.40g (9.45mmol) of 7 in 50mL of MeOH. After 48hat rt, the mixture was filtered over slica and by evaporation 1.24g (90%) of compound 8 was isolated.
The synthetic route of 58442-17-4 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Alvarez, Raquel; Gajate, Consuelo; Puebla, Pilar; Mollinedo, Faustino; Medarde, Manuel; Pelaez, Rafael; European Journal of Medicinal Chemistry; vol. 158; (2018); p. 167 – 183;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem