Reference of 65039-05-6, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 65039-05-6 as follows.
General procedure: 1-Butyl-3-methylimidazolidine, chloride salt (5 mmol), selenium (5 mmol), potassium carbonate (10 mmol), ethanol or acetone (5 mL) and a magnetic stirring bar were placed in a 50 mL, two-necked flask. Then the reaction mixture was vigorously stirred under reflux for the given times (see Table 2). After the reaction was complete, the resultant mixture was filtered, and the solvent evaporated under reduced pressure. Further purification by column chromatography on silica gel gave the pure product. All the products were characterised by NMR and HRMS.
According to the analysis of related databases, 65039-05-6, the application of this compound in the production field has become more and more popular.
Reference:
Article; Tian, Fengshou; Chen, Yahong; Wu, Lan; Li, Peng; Lu, Shiwei; Journal of Chemical Research; vol. 38; 6; (2014); p. 375 – 377;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem