In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 65039-05-6 as follows. category: imidazoles-derivatives
Add to a 100 mL round bottom flaskGlyphosate 1.69g (10mmol),Methanol (40 mL) and potassium hydroxide 0.62 g (11 mmol),Magnetic stirring at 50C,After the reaction solution is clarified,1-butyl-3-methylimidazolium iodide 2.66 g (10 mmol) was added,The reaction was stirred at room temperature for 0.75 hours.Dichloromethane (3 x 20 mL) was added for extraction.After the extraction is completed,The organic phase is washed once with saturated saline solution.Distilled and washed onceRotary evaporation,And dried in a vacuum drying oven to give a yellow oily liquid,Yield 90%.
According to the analysis of related databases, 65039-05-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Zhejiang Academy Of Agricultural Sciences; Yu Jianzhong; He Hongmei; Zhang Changpeng; Xu Zhenlan; Wu Min; Zhang Chunrong; He Kaiyu; Zhu Yahong; Yu Ruixian; Zhao Hua; (8 pag.)CN107987104; (2018); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem