Introduction of a new synthetic route about 5851-49-0

The synthetic route of 5851-49-0 has been constantly updated, and we look forward to future research findings.

Related Products of 5851-49-0, A common heterocyclic compound, 5851-49-0, name is 2-Heptyl-1H-benzo[d]imidazole, molecular formula is C14H20N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

2-Heptyl-benzimidazole (0.09 g, 0.42 mmol) was dissolved in acetonitrile (5 mL), potassium hydroxide (0.03 g, 0.53 mmol) was added and the mixture was refluxed for 30 min. 2-(Bromomethyl)naphthalene (0.11 g, 0.50 mmol) was added and the mixture was refluxed overnight.

The synthetic route of 5851-49-0 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Shelton, Kerri L.; DeBord, Michael A.; Wagers, Patrick O.; Southerland, Marie R.; Williams, Travis M.; Robishaw, Nikki K.; Shriver, Leah P.; Tessier, Claire A.; Panzner, Matthew J.; Youngs, Wiley J.; Bioorganic and Medicinal Chemistry; vol. 25; 1; (2017); p. 421 – 439;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem