Application of 184098-19-9, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 184098-19-9, name is 3-(2-Methyl-1H-imidazol-1-yl)aniline belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.
To 5-chloropyrazolo[l,5-a]pyrimidine-3-carbaldehyde (39 mg, 0.215 mmol) in dioxane was added 3-(2-methyl-lH-imidazol-l-yl)aniline (90 mg, 0.520 mmol). The mixture was heated in microwave (200 W) for 50 minutes at 120 C. The solid formed was isolated by filtration and air dried to yield 48 mg 5-(3-(2-methyl-lH-imidazol-l- yl)phenylamino)pyrazolo[l,5-a]pyrimidine-3-carbaldehyde (70%> yield). LCMS (M+l=319)
The synthetic route of 3-(2-Methyl-1H-imidazol-1-yl)aniline has been constantly updated, and we look forward to future research findings.
Reference:
Patent; CYLENE PHARMACEUTICALS INC.; HADDACH, Mustapha; RYCKMAN, David; RAFFAELE, Nicholas; WO2011/31979; (2011); A1;,
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