Adding a certain compound to certain chemical reactions, such as: 6953-65-7, name is (6-Chloro-1H-benzo[d]imidazol-2-yl)methanol, belongs to imidazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6953-65-7, COA of Formula: C8H7ClN2O
General procedure: NaOH (9.5 mmol) was added to a stirring solution of benzimidazole (6.7 mmol) in 10 mL ofEtOH/H2O 3:1 (v/v). Dimethyl sulfate (9.5 mmol) was added dropwise over 5 min and the mixturewas stirred for additional 2 h. Solvents were evaporated to give colorless solid, which wascrystallized from methanol to give corresponding product.
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Reference:
Article; Ryabukhin, Dmitry S.; Turdakov, Alexey N.; Soldatova, Natalia S.; Kompanets, Mikhail O.; Ivanov, Alexander Yu.; Boyarskaya, Irina A.; Vasilyev, Aleksander V.; Beilstein Journal of Organic Chemistry; vol. 15; (2019); p. 1962 – 1973;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem