Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5098-11-3, name is 5-Amino-1H-imidazole-4-carbonitrile, This compound has unique chemical properties. The synthetic route is as follows., Product Details of 5098-11-3
Example 28: General procedure for the preparation of 4-methyl-benzoyl- imidazo[1 ,5-a]pyrimidines of general formula (I) following Scheme 1 N-[3-[8-(4-methyl-benzoyl)-imidazo[1 ,5-a]pyrimidin-4-yl]-phenyl]-N-methyl- methanesulfonamidePart AA solution of 4-methyl-phenyl magnesium bromide was prepared from 1.0 g ( 42 mmol) of magnesium and 7.2 g (42 mmol) of 1 -bromo-4-methyl-benzene in 40 ml of dry tetrahydrofuran. To the solution of the Grignard reagent, cooled by an ice-salt bath, a mixture of 1 g (9.3 mmol)of 5-amino-1 H-imidazole-4-carbonitrile and 20 ml of dry tetrahydrofuran was slowly added with stirring. After standing at room temperature for 2 hours, the mixture was cooled and decomposed by adding, with stirring, 40 ml of 3M hydrochloric acid. When the decomposition was completed (1 hour at a temperature between 90-950C), the reaction mixture was basified to pH 10 with 25% ammonium hydroxide and was extracted with methylene chloride. The solution was dried with anhydrous sodium sulfate and the methylene chloride was distilled under diminished pressure to yield an oil which was chromatographied (silica gel) using methylene chloride/methanol as eluent to produce 1.11 g (yield 61%) of (5-amino-1 H- imidazol-4-yl)-p-tolyl-methanone. 1H NMR (400 MHz, DMSO): . . 2.33 (3H, s), 6,3155 (4H, m), 8.27 (1 H, s). EPO
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 5098-11-3.
Reference:
Patent; FERRER INTERNACIONAL, S. A.; WO2006/84835; (2006); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem