Reference of 30086-64-7, A common heterocyclic compound, 30086-64-7, name is Hexahydro-1H-benzo[d]imidazole-2(3H)-thione, molecular formula is C7H12N2S, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of cyclic thiourea 4a-e (1 mmol) and di(methylsulfanyl)methylenemalononitrile 5a (0.170 g, 1 mmol) in DMF (3 mL) was stirred at 120 C. Upon completion (3 h monitored by TLC), the solvent was removed by rotary evaporator under vacuum. The afforded orange solid washed by ethyl acetate and dried to give 1.
The synthetic route of 30086-64-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Alizadeh, Abdolali; Vahabi, Amir Hossein; Bazgir, Ayoob; Khavasi, Hamid Reza; Zhu, Zhe; Zhu, Long-Guan; Tetrahedron; vol. 72; 10; (2016); p. 1342 – 1350;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem