Related Products of 37619-25-3, The chemical industry reduces the impact on the environment during synthesis 37619-25-3, name is Methyl 1H-benzo[d]imidazole-4-carboxylate, I believe this compound will play a more active role in future production and life.
Into a 100-mL round-bottom flask, was placed a solution of methyl 1H-1,3- benzodiazole-4-carboxylate (500 mg, 2.84 mmol, 1.00 equiv) in N,N-dimethylformamide (60 mL), potassium carbonate (1.1 g, 7.96 mmol, 3.00 equiv), and (2-chloroethyl)dimethylamine hydrochloride (523.6 mg, 3.64 mmol, 1.00 equiv). The resulting solution was stirred overnight at 60 oC in an oil bath then allowed to cool and diluted with 40 mL of sodium chloride (aq). The resulting mixture was extracted with 2×40 mL of ethyl acetate and the organic layers combined and dried over anhydrous sodium sulfate then concentrated under vacuum. The residue was applied onto a silica gel column and eluted with ethyl acetate/petroleum ether (1:2). This resulted in 100 mg (14%) of methyl 1-[2-(dimethylamino)ethyl]-1H-1,3- benzodiazole-4-carboxylate as a solid
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, Methyl 1H-benzo[d]imidazole-4-carboxylate, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; LYCERA CORPORATION; AICHER, Thomas, Daniel; PADILLA, Fernando; TOOGOOD, Peter, L.; CHEN, Shoujun; (331 pag.)WO2016/138335; (2016); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem