Application of 30086-64-7,Some common heterocyclic compound, 30086-64-7, name is Hexahydro-1H-benzo[d]imidazole-2(3H)-thione, molecular formula is C7H12N2S, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: A mixture of alkyl chloroglyoxalates (5 mmol), cyclohexyl isocyanide (Cy-CN,5 mmol), and thiourea derivatives (5 mmol) was added to a mixture of GO-H2PO4(0.1 g) in acetonitrile for 2 h at 50 C. The catalyst was removed by filtration, and the solvent was evaporated to yield 4-hydroxy-thiazolidine-4-carboxylates. All products are solid and purified by recrystallization in ethanol.
The synthetic route of 30086-64-7 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Abdouss, Majid; Asadi, Elham; Daghlavi, Amneh; Ghasemi, Mohammad Hadi; Kowsari, Elaheh; Research on Chemical Intermediates; (2020);,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem