26530-93-8, name is 1-Methyl-1H-benzo[d]imidazol-6-amine, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. HPLC of Formula: C8H9N3
General procedure: Procedure A: The isothiocyanate compound (1 equiv) was added to the solution of amine (1 equiv) in 5 ml of a mixture of dichloromethane and acetonitrile (1:1, v/v). The mixture was cooled to 0°C. Then, triethylamine (2 equiv) was added gradually. The mixture was stirred at 0°C for 15 min, after which stirring was continued at room temperature for 2?10 h. The reaction mixture was concentrated, extracted with dichloromethane, and washed with brine.The organic layer was dried over MgSO4 and purified by column chromatography (MeOH/CH2Cl2) or by preparative TLC (MeOH/CH2Cl2) to afford the desired product.
The synthetic route of 26530-93-8 has been constantly updated, and we look forward to future research findings.