Continuously updated synthesis method about 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole

The chemical industry reduces the impact on the environment during synthesis 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole. I believe this compound will play a more active role in future production and life.

Reference of 914306-50-6, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 914306-50-6, name is 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole, This compound has unique chemical properties. The synthetic route is as follows.

3.50 g (11.5 mmol) of 1-(2,6-diisopropylphenyl)-2-phenyl-1H-imidazole are initially charged in 200 ml of 2-ethoxyethanol/water (ratio 3/1) and admixed with 1.84 g (5.2 mmol) of iridium(III) chloride trihydrate. The reaction mixture is heated at reflux for 18 h. After cooling, 50 ml of distilled water are added. The precipitate is filtered off, washed with distilled water and dried. This gives 3.50 g (80%) of ?-dichloro dimer D1 as a yellow powder. 1H NMR (CD2Cl2, 400 MHz):delta=0.95 (d, 12H), 1.18 (d, 12H), 1.27 (d, 12H), 1.34 (d, 12H), 2.80-2.91 (m, 8H), 6.08 (d, 4H), 6.24 (d, 4H), 6.39 (pt, 4H), 6.53 (pt, 4H), 6.97 (d, 4H), 7.39-7.45 (m, 8H), 7.59 (t, 4H), 7.67 (d, 4H).

The chemical industry reduces the impact on the environment during synthesis 1-(2,6-Diisopropylphenyl)-2-phenyl-1H-imidazole. I believe this compound will play a more active role in future production and life.