Brief introduction of 5-Phenyl-1H-imidazole-2-carbaldehyde

The synthetic route of 56248-10-3 has been constantly updated, and we look forward to future research findings.

Synthetic Route of 56248-10-3, A common heterocyclic compound, 56248-10-3, name is 5-Phenyl-1H-imidazole-2-carbaldehyde, molecular formula is C10H8N2O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: To a stirred solution of compound 3 (100mg, 0.40 mmol) in ethanol was added corresponding benzohydrazides (4a-m) (1.0 mmol) and refluxed for 1 h. The reaction mass was washed with pet ether, filtered and dried undervacuum to obtain the pure hydrazone compounds. Yields ofthe products varied between 78 and 88 %.

The synthetic route of 56248-10-3 has been constantly updated, and we look forward to future research findings.