Application of 10364-94-0, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 10364-94-0 as follows.
General procedure: To a stirred solution of NaSH (9 mmol, 3 equiv.) in water (4 mL) was added N-acyl benzotriazole 1 (3 mmol, 1 equiv.). The reaction mixture was stirred at room temperature for 3 h. After completion of the reaction, HCl (2N) was added dropwise to acidify the solution. The precipitated solid was collected by vacuum filtration, washed with water (10 mL), and dried. In case of oily residue, the aqueous solution was decanted, and the residue was dissolved in EtOAc (15 mL). This solution was washed with 10% HCl (2 × 10 mL), brine (10 mL), dried over MgSO4, and concentrated under reduced pressure. These compounds are oils at room temperature but usually solidify after refrigeration.
According to the analysis of related databases, 10364-94-0, the application of this compound in the production field has become more and more popular.