In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 96797-15-8, name is 4-Iodo-1-trityl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. Computed Properties of C22H17IN2
Step 11C 62ATo a solution of 4-iodo-trityl-imidazole (6.77 g, 15.5 mmol) in DCM (100 ml_) was added EtMgBr (3.0M in Et2O, 4.96 mL, 14.9 mmol) slowly at -200C, stirred at – 200C for 30 min. A solution of 1C (2.8 g, 13.5 mol) in DCM (20 mL) was added very slowly. The mixture was stirred at RT for 1 h, quenched with saturated NH4CI, diluted with DCM. The DCM layer was washed with brine, dried and concentrated. Flash chromatography (EtOAc/Hexanes, 1 :2 then 10:1 ) afforded 62A (5.0 g, 72%).
The synthetic route of 96797-15-8 has been constantly updated, and we look forward to future research findings.