Month: April 2021

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 3543-72-4, Name is Ethyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate, molecular formula is C14H17N3O4. In an article, author is Kumar, C. Anil,once mentioned of 3543-72-4, HPLC of Formula: C14H17N3O4.

Pro-apoptotic activity of imidazole derivatives mediated by up-regulation of Bax and activation of CAD in Ehrlich Ascites Tumor cells

In this study we report that, imidazole derivatives can induce apoptosis in Ehrlich ascites tumor (EAT) cells, which is clearly evident from annexin-V staining, flow cytometric analysis of cell cycle phase distribution and DNA fragmentation. Delineating further into molecular mechanisms leading to apoptosis of EAT cells, we observed that imidazole derivatives induce tumor cell death by the up-regulation of proto-oncoprotein Bax, release of cytochrome c from the mitochondria which activates caspase-3 and activated caspase-3 activates CAD (Caspase Activated DNase) causes DNA fragmentation. The status of Bcl-2 remains unaltered in EAT cells, and the under expression of Bcl-2 and up-regulation of Bax resulted in the increase of Bax: Bcl-2 ratio suggesting that Bcl-2 family involved in the control of apoptosis. These results suggest a further possible clinical application of imidazole derivatives as pro-apoptotic agent in association with conventional chemotherapeutic agents.

Interested yet? Keep reading other articles of 3543-72-4, you can contact me at any time and look forward to more communication. HPLC of Formula: C14H17N3O4.

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 641571-11-1, Name is 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline, molecular formula is , belongs to imidazoles-derivatives compound. In a document, author is Jayabharathi, Jayaraman, Quality Control of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline.

A study on the binding interaction between the imidazole derivative and bovine serum albumin by fluorescence spectroscopy

The interaction between the imidazole derivative 2-(2,4-difluorophenyl)-1-phenyl-1H-imidazo[4,5-f] [1,10]phenanthroline (dfppip) and bovine serum albumin (BSA) was investigated by fluorescence and UV-vis absorbance spectroscopy. From the experimental results, it was found that the imidazole derivative has strong ability to quench the intrinsic fluorescence of BSA by forming complexes. Electrostatic interactions play an important role to stabilize the complex. The binding constants and the number of binding sites have been determined in detail. The distance (r) between the donor and the acceptor was obtained according to fluorescence resonance energy transfer (FRET). Conformational changes of BSA were observed from synchronous fluorescence spectroscopy. The effect of metal ions such as Cu2+, Zn2+, Ca2+, Mg2+, Ni2+, Co2+ and Fe2+ on the binding constants between the imidazole derivative and BSA were also studied. (C) 2011 Elsevier B.V. All rights reserved.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 641571-11-1, in my other articles. Quality Control of 3-(4-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)aniline.

Electric Literature of 3543-73-5, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, SMILES is O=C(OCC)CCCC1=NC2=CC(N)=CC=C2N1C, belongs to imidazoles-derivatives compound. In a article, author is Ramkumar, Sowmya, introduce new discover of the category.

Enhanced corrosion resistance of mild steel in sulphuric acid medium by imidazole derivative: Experimental and computational studies

The inhibition action of the imidazole derivative on the corrosion of mild steel in 0.5 M Sulphuric acid was investigated by weight loss, polarization, Impedance and SEM. The PZC of mild steel was studied by AC impedance method. The polarization experiment revealed that IDZ is of mixed-type but slightly anodic control. Weight loss results obtained revealed that the imidazoline derivatives performed excellently as corrosion inhibitor with efficiency above 70% at 20ppm at 303 K. The optimum period of inhibition for IDZ was determined by weight loss studies. Its adsorption on mild steel obeys Tempkin isotherm. Quantum chemical parameters and Mulliken charge densities on the optimized structure of imidazoline derivative were calculated using GAUSSIAN 09 with B3LYP / 6-31G (d,p) basis set. (C) 2019 Elsevier Ltd. All rights reserved.

Electric Literature of 3543-73-5, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 3543-73-5.

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 616-47-7, Name is 1-Methyl-1H-imidazole, molecular formula is C4H6N2, belongs to imidazoles-derivatives compound. In a document, author is Jayabharathi, Jayaraman, introduce the new discover, Formula: C4H6N2.

Fluorescence spectral studies of some imidazole derivatives

The photophysical properties of imidazole derivatives namely 2-(2,4-difluorophenyl)-4,5-dimethyl-1-p-tolyl-1H-imidazole and N,N-dimethyl-4-(4,5-dimethyl-2-phenyl-1H-imidazol-1-yl)benzenamine,synthesized from an unusual four components assembling, were studied in several solvents. Polarization also plays major role in the increase of excited-state dipole moment (mu(e)). From the spectral results, it was found that there is equilibrium between neutral species and monocationic (MC) species in polar aprotic and polar protic solvents. The basicity of the solvent, C-beta or C-SB has a negative value, suggesting that the absorption and fluorescence bands shift to lower energies with increasing electron-donating ability of the solvent. Therefore, resonance structures 1b and 2b has the positive charge located at the nitrogen atom stabilized in basic solvents. (C) 2012 Elsevier B.V. All rights reserved.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 616-47-7. Formula: C4H6N2.

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 820959-17-9, Name is Ac-Beta-Ala-His-Ser-His-OH, SMILES is CC(NCCC(N[C@@H](CC1=CNC=N1)C(N[C@@H](CO)C(N[C@@H](CC2=CNC=N2)C(O)=O)=O)=O)=O)=O, belongs to imidazoles-derivatives compound. In a document, author is Otmacic, H, introduce the new discover, COA of Formula: C20H28N8O7.

Copper corrosion inhibitors in near neutral media

The efficiency of nontoxic imidazole derivatives as copper corrosion inhibitors in sodium chloride solutions was studied by electrochemical polarization methods (Tafel extrapolation and polarization resistance method) and weight-loss measurements. Results obtained during this study show that inhibitors with higher molecular weight, especially those with a phenyl ring, have better inhibiting properties. The values of free energy of adsorption, as calculated from Freundlich isotherm, indicate that investigated imidazole derivatives physisorbe on the copper surface. (C) 2002 Elsevier Science Ltd. All rights reserved.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 820959-17-9 is helpful to your research. COA of Formula: C20H28N8O7.

Electric Literature of 820959-17-9, Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. 820959-17-9, Name is Ac-Beta-Ala-His-Ser-His-OH, SMILES is CC(NCCC(N[C@@H](CC1=CNC=N1)C(N[C@@H](CO)C(N[C@@H](CC2=CNC=N2)C(O)=O)=O)=O)=O)=O, belongs to imidazoles-derivatives compound. In a article, author is Safa, Kazem D., introduce new discover of the category.

Synthesis of 2-aryl-1,1-bis(silyl)alkenes-containing tetrasubstituted imidazoles catalysed by M-Cu/ZSM-5 (M: Cr, Mn, Co, Ni, V, Zn and Fe) zeolites-supported bimetallic nanostructures

The one-pot synthesis of tetrasubstituted imidazoles by using a series of M-Cu/ZSM-5 (M: Cr, Mn, Co, Ni, V, Zn and Fe) zeolites-supported bimetallic catalysts was studied. Fe-Cu/ZSM-5 bimetallic oxide catalyst had the highest activity in improving the efficiency of the heterogeneous cyclo-condensation reaction. Some imidazole derivatives terminated by vinylbis(silanes) have been synthesised using (Me3Si)(3)CLi through the Peterson olefination reaction.

Electric Literature of 820959-17-9, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 820959-17-9 is helpful to your research.

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels. 144689-94-1, Name is Diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate, molecular formula is C12H18N2O4. In an article, author is Dias, Gleiston G.,once mentioned of 144689-94-1, Product Details of 144689-94-1.

Rhodium(III)-Catalyzed C-H/N-H Alkyne Annulation of Nonsymmetric 2-Aryl (Benz)imidazole Derivatives: Photophysical and Mechanistic Insights

Rhodium(III) catalysis enabled C-H/N-H alkyne annulation of nonsymmetric imidazole derivatives. This study encompasses the synthesis of imidazoles from a naturally occurring quinoidal compound and their use for the preparation of rigid pi-extended imidazole derivatives with outstanding fluorescence. Our study also brings to light the photophysical aspects and the mechanism of the reaction studied via computational calculations. This method provided an efficient and versatile tool for the synthesis of fluorescent compounds with a wide range of chemical and biological applications.

Interested yet? Keep reading other articles of 144689-94-1, you can contact me at any time and look forward to more communication. Product Details of 144689-94-1.

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , COA of Formula: C9H13N7, 38668-46-1, Name is 6-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-1,3,5-triazine-2,4-diamine, molecular formula is C9H13N7, belongs to imidazoles-derivatives compound. In a document, author is Jayabharathi, J., introduce the new discover.

High efficiency, blue emitting materials based on phenanthro [9,10-d]imidazole derivatives

The blue light emitting materials based on a fluoro phenanthro [9,10-d] imidazole derivatives prepared by a facial synthetic process exhibit good thermal stability, highly efficient fluorescence and balanced carrier injection. The multi-layered device based on fluoro phenanthroimidazole derivatives shows a higher luminance in a lower turn-on voltage. The device performance implies that the phenanthroimidazole unit is an excellent building block for tuning the carrier injection properties as well as blue emission. (C) 2014 Elsevier B.V. All rights reserved.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 38668-46-1. COA of Formula: C9H13N7.

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 23996-25-0, Name is 2-Ethyl-4-methyl-1H-imidazole-1-propanenitrile, SMILES is CCC1=NC(C)=CN1CCC#N, in an article , author is Rossi, Renzo, once mentioned of 23996-25-0, COA of Formula: C9H13N3.

Current Advances in the Synthesis and Biological Evaluation of Pharmacologically Relevant 1,2,4,5-Tetrasubstituted-1H-Imidazole Derivatives

In recent years, the synthesis and evaluation of the biological properties of 1,2,4,5-tetrasubstituted-111-imidazole derivatives have been the subject of a large number of studies by academia and industry. In these studies it has been shown that this large and highly differentiated class of heteroarene derivatives includes high valuable compounds having important biological and pharmacological properties such as antibacterial, antifungal, anthelmintic, anti-inflammatory, anticancer, antiviral, antihypertensive, cholesterol-lowering, antifibrotic, antiuricemic, antidiabetic, antileishmanial and antiulcer activities. The present review with 411 references, in which we focused on the literature data published mainly from 2011 to 2017, aims to update the readers on the recent developments on the synthesis and biological evaluation of pharmacologically relevant 1,2,4,5-tetrasubstituted-lff-imidazole derivatives with an emphasis on their different molecular targets and their potential use as drugs to treat various types of diseases. Reference was also made to substantial literature data acquired before 2011 in this burgeoning research area.

Interested yet? Read on for other articles about 23996-25-0, you can contact me at any time and look forward to more communication. COA of Formula: C9H13N3.

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 693-98-1, Name is 2-Methyl-1H-imidazole, SMILES is CC1=NC=CN1, belongs to imidazoles-derivatives compound. In a document, author is El-Haddad, Mahmoud N., introduce the new discover, Safety of 2-Methyl-1H-imidazole.

Electroanalytical, quantum and surface characterization studies on imidazole derivatives as corrosion inhibitors for aluminum in acidic media

In this study, the effect of imidazole derivatives on the inhibition of aluminum corrosion in 0,5 M HCl has been studied using potentiodynamic polarization, electrochemical impedance spectroscopy (EIS) and electrochemical frequency modulation (EFM) measurements. The results show that all imidazole derivatives are good inhibitors, and inhibition efficiency follows the order: 8> A. Polarization curves demonstrated that the imidazole derivatives were of mixed-type inhibitors. The adsorption of each inhibitor on aluminum surface obeys Frumkin adsorption isotherm. Surface morphology studies were done using scanning electron microscopy (SEM) to characterize the film formed on aluminum surface. Quantum chemical calculations show that imidazole derivatives can adsorb on the aluminum surface through the nitrogen atoms as well as it-electrons in the imidazole ring. (C) 2015 Elsevier B.V. All rights reserved.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 693-98-1 is helpful to your research. Safety of 2-Methyl-1H-imidazole.