Reference of 26576-46-5,Some common heterocyclic compound, 26576-46-5, name is 5-Acetoacetlamino benzimdazolone, molecular formula is C11H9N3O3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Dispersion synergist SYN-23; Formation of the dispersion synergist SYN-23 is accomplished by diazotation of compound 30 and subsequent coupling with compound 3 according to the following synthesis scheme: [Show Image] 29.98 mL (0.36 mol) of concentrated hydrochloric acid was added to a suspension of 18.1 g (0.1 mol) of compound 30 in 300 mL methanol. The mixture was cooled to about 0-5C and 8.97 g (0.13 mol) of sodiumnitrite was added. The diazonium-salt was kept at a temperature between 0 and 5C. After 15 minutes the excess of nitrite was neutralized by adding 3.0 g (0.03 mol) of sulfamic acid and a pH of 7 was obtained by adding 25.2 g (0.3 mol) of sodiumcarbonate. While the diazonium-salt was made, 22.1 g (0.1 mol) of compound 3 was dissolved in a mixture of 500 mL methanol and 10.0 mL (0.1 mol) 29% soduimhydroxide-solution. This solution was dropped into the diazonium-salt solution and a yellow suspension appears. The temperature was maintained between 0 and 5C for about 3 hours and the yellow pigment was filtered and washed with methanol. The yield was 88 %.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 5-Acetoacetlamino benzimdazolone, its application will become more common.