Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 14486-52-3, name is 1-Methyl-2-(methylthio)imidazole, A new synthetic method of this compound is introduced below., SDS of cas: 14486-52-3
A. 2-Methylthio-3-methyl-1-(2-mercaptoethyl)imidazolium trifluoromethanesulfonate STR193 Trifluoromethanesulfonic acid (1.38 mL, 0.015 mol) was added dropwise to 2-methylthio-1-methylimidazole1 (4.0 g), 0.03 mol) at 0 C. under N2. Ethylene sulfide (0.9 mL, 0.015 mol) was then added and the mixture was heated at 55 C. under N2 for 24 h. The reaction mixture was triturated with ether (3x) and the residue was taken up in acetone, filtered and evaporated. This gave the product (4.2 g, 82%) as a semicrystalline solid which was used as such without further purification. ir(film) numax: 2550 (w, sh) cm-1; ‘Hnmr (d6 -acetone) delta: 7.97 (s, 2H), 4.66 (t, J=7 Hz, 2H, methylene), 4.17 (s, 3H, N-Me), 3.20 (d of t, J=7 Hz, J’=9 Hz, 2H, methylene), 2.72 (s, 3H, S-Me), 2.20 (t, J =9 Hz, 1H, –SH).
The synthetic route of 14486-52-3 has been constantly updated, and we look forward to future research findings.