621-72-7, name is 2-Benzyl-1H-benzo[d]imidazole, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Quality Control of 2-Benzyl-1H-benzo[d]imidazole
Under an oxygen atmosphere, 0.30 mmol of 2-benzylbenzimidazole (1 g) and 2 mL of dimethyl sulfoxide were sequentially added to the Schlenk reaction tube.The reaction was stirred under constant temperature in an IKA (constant temperature heating magnetic stirrer) for 48 h. After the reaction is completed, it is cooled to room temperature. Quenched with distilled water.It was then extracted with ethyl acetate (3 x 20 mL). The organic layers were combined and dried over anhydrous sodium sulfate. Pure target product by column chromatography 2g (52.6mg, 79%).
The synthetic route of 621-72-7 has been constantly updated, and we look forward to future research findings.