Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3273-68-5, name is 4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)butanoic acid, This compound has unique chemical properties. The synthetic route is as follows., name: 4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)butanoic acid
Part A. Preparation of chloro 2,3-dihydro-2-oxo-1H-benzimidazol-1-butanoate. Dichloromethane (3772 L) and then 4-(2-oxo-2,3-dihydrobenzimidazol-1-yl)butyric acid (525 kg; 2.4 kmol) were charged to a stirred-tank reactor, followed by N,N-dimethylformamide (21 L). The resulting mixture was cooled to 10 C. Afterward, oxalyl chloride (326.8 kg)) was dosed at 10-15 C. over 2-3 hours while stirring. The resulting mixture was then stirred at 15-20 C. for an additional 1-3 hours. All the above steps were conducted under a N2 atmosphere. Conversion was checked by in-process control (“IPC?).
According to the analysis of related databases, 3273-68-5, the application of this compound in the production field has become more and more popular.